I should have expanded a little. Many of the big companies (including Nintendo) don't accept unsolicited submissions.
The major film studios have the same policy, but I had an interesting experience with an award nominated animation script a few years ago.
I tried to get the screenplay to Pixar & DreamWorks via go-betweens and independent producers who had worked with them for a long time, but I was unsuccessful. But during my research I did 'accidentally' obtain the direct email address of a major director working at 21st Century Fox. They don't consider unsolicited submissions either, but I was so frustrated I thought, what the hell, and sent a short email with the logline for the script.
Within five minutes I had two emails from different members of the Fox legal team saying they don't accept unsolicited emails, my message would be destroyed and, anyway, they may be working on an identical story, and if so, it was entirely a coincidence (I have another story about this subject, but won't bore you further). Oh, and don't do it again!
Five minutes later, I got an email from the director requesting the screenplay via my agent. I didn't have an agent, but I did use an LA lawyer for submitting when I needed a rep, so I got the script to the guy. They didn't buy it, but it bounced around the senior decision-makers at Fox for a couple of very heady weeks.
I learned that companies that do not take unsolicited material are absolutely rigid about enforcing that policy. Unless they like the submission