I cut my teeth on Heinlein , Asimov and Clarke , in the 1950s, and I still love them, at one time they would have been in my top ten , when I got into my 20s in the 1960 I put Ted Sturgeon, in particular More Than Human in my to spot , it stayed there until 1969 and Left Hand of Darkness. No nothing like since, I love Chad Olivers' "Blood's a Rover" but it's not the same.
Left Hand of Darkness is SF's most unique novel.
I'm not familiar with Ted Sturgeon or Chad Oliver's. I'll toss those books on my endless and eternal "To Read" list.
The Left Hand of Darkness is still one of my all time favorite books. I tend to be slow to finish the work of authors I love and, as such, haven't read all of Le Guin's. I'm dragging it out, especially since she is no longer with us. I think The Dispossessed is next.